Ketchikan Harbor Seaplane Base (IATA: WFB, FAA LID: 5KE) is a privately owned, public use seaplane base located at the harbor of Ketchikan, a city in the Ketchikan Gateway Borough of the U.S. state of Alaska. It is located near the Ketchikan International Airport, which also has its own seaplane landing area. Prior to the opening of the Ketchikan International Airport in 1973, scheduled passenger seaplane service was operated with amphibian aircraft between the seaplane base and the Annette Island Airport located approximately 20 miles south, as this land plane airfield previously served as the primary airport for Ketchikan, with scheduled airline flights being operated by Pan American World Airways, Pacific Northern Airlines and Western Airlines into Annette Island over the years.

As per Federal Aviation Administration records, the airport had 38,945 passenger boardings (enplanements) in calendar year 2008, 40,462 enplanements in 2009, and 43,737 in 2010.