Francis E. Warren Air Force Base (ICAO: KFEW, FAA LID: FEW), shortened as F.E. Warren AFB is a United States Air Force base (AFB) located approximately 3 miles (4.8 km) west of Cheyenne, Wyoming. It is one of three strategic-missile bases in the U.S. It was named in honor of Francis E. Warren in 1930. Warren AFB is home of the 90th Missile Wing (90 MW), assigned to the Twentieth Air Force, Air Force Global Strike Command. The 90 MW operates the LGM-30G Minuteman III ICBM. It is also the home of Twentieth Air Force, which commands all U.S. Air Force ICBMs.

Warren AFB is the oldest continuously active military installation within the Air Force, established in 1867 (157 years ago) by the United States Army as Fort David Allen Russell. The facility came under the control of the United States Army Air Forces on 1 June 1947, and then of the United States Air Force (USAF) on 18 September 1947.

The 90th Missile Wing is commanded by Colonel Johnny L. Galbert. Twentieth Air Force, co-located at Warren AFB, is under the command of Major General Michael Lutton. Warren AFB is a census-designated place and had a resident population of 3,072 at the 2010 census.