Patrick Space Force Base (IATA: COF, ICAO: KCOF, FAA LID: COF) is a United States Space Force installation located between Satellite Beach and Cocoa Beach, in Brevard County, Florida, United States. It is named in honor of Major General Mason Patrick, USAAC. It is home to Space Launch Delta 45 (SLD 45), known as the 45th Space Wing (45 SW) when it was part of the Air Force. In addition to its "host wing" responsibilities at Patrick SFB, the 45 SW controls and operates Cape Canaveral Space Force Station (CCSFS) and the Eastern Range. It was originally opened and operated from 1940 to 1947 as Naval Air Station Banana River, a U.S. Navy airfield. It was then deactivated as a naval installation in 1947 and placed in caretaker status until it was transferred to the Air Force in late 1948.

Additional tenant activities at Patrick SFB include the 920th Rescue Wing, the Air Force Technical Applications Center, and the Defense Equal Opportunity Management Institute (DEOMI). Total employment is 10,400. There are 13,099 military, dependents, civilian employees, and contractors on base.

The base is a census-designated place (CDP) and had a resident population of 1,642 as of the 2020 census, up from 1,222 at the 2010 census. It is part of the Palm Bay—Melbourne—Titusville, Florida Metropolitan Statistical Area.