Manhattan Regional Airport (IATA: MHK, ICAO: KMHK, FAA LID: MHK) in Riley County, Kansas, United States, is the second-busiest commercial airport in Kansas. Owned by the city of Manhattan, Kansas,the airport is located about five miles southwest of downtown Manhattan. American Airlines serves the airport with five daily flights to Chicago O'Hare International Airport and Dallas/Fort Worth International Airport.The airport also accommodates general aviation and charter planes for the military and college sports teams, being conveniently located four miles east of Fort Riley and eight miles southwest of Kansas State University's athletic complex).

The National Plan of Integrated Airport Systems for 2013–2017 categorized it as a primary commercial service airport (more than 10,000 enplanements per year).

Traffic at the airport multiplied after American Eagle began its service in August 2009. Between 2008 and 2012, Federal Aviation Administration records show that annual passenger boardings (enplanements) at the airport grew from 16,489 to more than 69,000. The most recent statistics show 70,705 enplanements in 2018.