Mountain Home Air Force Base (IATA: MUO, ICAO: KMUO, FAA LID: MUO) is a United States Air Force (USAF) installation in the western United States. Located in southwestern Idaho in Elmore County, the base is twelve miles (20 km) southwest of Mountain Home, which is forty miles (65 km) southeast of Boise via Interstate 84. The base is also used by the Republic of Singapore Air Force (RSAF), which has a detachment of F-15SG combat aircraft on long term assignment to the base and a squadron composed of RSAF and USAF personnel.

Constructed in the early 1940s during World War II as a training base for bombers, after the war it briefly had transports, then was a bomber and missile base. It became a fighter base in 1966. The host unit at Mountain Home has been the 366th Fighter Wing (366 FW) of the Air Combat Command (ACC), nicknamed the Gunfighters, since 1972. The base's primary mission is to provide combat airpower and support for worldwide contingency operations.

Part of the base is a census-designated place (CDP); the population was 3,238 at the 2010 census.