Presque Isle International Airport (IATA: PQI, ICAO: KPQI, FAA LID: PQI), formally Northern Maine Regional Airport at Presque Isle, is a mile northwest of Presque Isle, in Aroostook County, Maine, United States. It serves the residents of Presque Isle and a vast area of northern Maine and northwestern New Brunswick. Airline flights to Newark Liberty International Airport are subsidized by the federal government's Essential Air Service program at a cost of $3,892,174 (per year).

Federal Aviation Administration records say the airport had 13,385 passenger boardings (enplanements) in calendar year 2008, 13,513 in 2009 and 15,052 in 2010. The National Plan of Integrated Airport Systems for 2011–2015 categorized it as a primary commercial service airport (more than 10,000 enplanements per year).

The airport has the third longest active runway in Maine at 7441' (behind Bangor International Airport, 11,440' and Brunswick Executive Airport, formerly Naval Air Station Brunswick runway 1R/19L, 8000'), and fifth longest overall (after the Loring Commerce Centre, formerly Loring Air Force Base (runway closed), 12,100', and Brunswick Executive Airport 1L/19R (runway closed), 8000'). It was once hub to Aroostook Airways, a commuter airline in the 1970s, with service to several cities throughout New England.