Dr. Luis María Argaña International Airport (IATA: ESG, ICAO: SGME) is an airport that serves the small city of Mariscal Estigarribia, in the Boquerón Department of Paraguay.

The airport is named after Luis María Argaña, a vice president who was assassinated in 1999. It is operated by Paraguayan military authorities. GlobalSecurity.org states that some believe the United States are using the airport as a permanent military base. However, they go on to say that this is false.

With 3,500 m (11,483 ft), its runway is the longest in the country, more than Asunción's airport.