One Biscayne Tower is an office skyscraper in Miami, Florida, United States. It is located on the eastern edge of Downtown Miami, on South Biscayne Boulevard. It comprises Class A office space completely. The office tower was acquired by CP Group in 2021 in a joint venture with Rialto Capital Management. The approximately 983,000 square feet building contains 39 floors and is 492 ft (150 m) tall, to the roof. The 200-foot (61 m) antenna mast on top of the building raises its total height, including antenna, to nearly 700 feet (210 m).

When built in 1972, it ended the Dade County Courthouse's 44-year reign as the tallest building in Miami. It held this status until the Southeast Financial Center was topped off in 1984. The building, although relatively short compared to many of the newer skyscrapers in Miami, remains a symbol of the city. It appears often on most postcards of the skyline and remains a signature building of Miami, due to its being a symbol of prosperity for the Cuban exile community.